The Irish Anti-Vivisection Society, SAFRIreland, NARA, Sentient Rights Ireland and The Party for Animal Welfare will be commemorating World Day for Animals in Laboratories on Wednesday April 24th at 13:00 in Dublin City Centre.
We will be highlighting the thousands of animals suffering in Irish laboratories with a leaflet drop outside the Stephen's Green shopping centre in Dublin City. Join us in spreading awareness and commemorating the suffering of millions of animals all over the world.
Botulinum toxin (Bt) is a neurotoxin which induces muscle paralysis by blocking neurotransmitters. Bt is used for treating medical conditions (such as migraines and lazy eye), and in cosmetic procedures to reduce the appearance of wrinkles.
The manufacture of Bt products is approved for medical purposes – and the use of animals in testing procedures is authorised for that reason. However, huge numbers of practitioners use them “off-label” for aesthetic treatments. “Off-label use” is known to be widespread, but it is not known what percentage is used for cosmetic versus medical applications. Indeed, there has been a documented surge in demand for Bt-based products within the cosmetic industry. In 2022, the International Society of Aesthetic Plastic Surgery estimated over 9 million “Botox” treatments were administered, a global increase of 26.1% compared to 7 million in 2021.
As Bt is a biological product, the potency of each batch needs to be tested and assured before it can be used in humans. The standard method, an LD50 assay using mice, determines the lethal dose that kills 50% of test animals. The increasing demand of Bt products has involved large numbers of animals undergoing ‘severe’ procedures.
Dr Dan Lyons Policy Consultant for The Irish Anti-Vivisection Society spoke to Neil Prendeville on Red FM about the high numbers of mice being used in Ireland to test for Botox. Tune in to Dan Lyons at 1 Hr 57 Mins
More than 90,000 animals were used for testing in Irish laboratories in 2022, according to the latest figures from the Health Products Regulatory Authority (HPRA). The study comes as animal rights groups continue to call for alternative ways to test medicines. In its annual report, the HPRA said mice were the most commonly used species for tests, at 72%, while rats, pigs, and sheep were also experimented on. The total number of uses of animals in testing overall was 92,939, while some animals were tested on more than once.
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Dr Dan Lyons Policy Consultant for The Irish Anti-Vivisection Society spoke to Newstalk Breakfast about severe poisoning tests for Botox.
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